• OpenAI has developed a GPT-4b micro AI model with Retro Biosciences to re-engineer Yamanaka factors for longevity research.
  • The GPT-4b micro model aims to transform human skin cells into youthful stem cells, advancing efforts to extend the human lifespan by 10 years.

OpenAI is venturing into longevity science through a collaboration with Retro Biosciences, a startup dedicated to extending the human lifespan by 10 years. According to the MIT Technology Review, OpenAI has developed a new AI model, GPT-4b micro, in partnership with Retro, marking its first major step into biological research.

Retro, which Sam Altman, has been working with the AI research company for roughly a year. The GPT-4b micro model is designed to re-engineer proteins, particularly a group called the Yamanaka factors. These proteins are known for converting human skin cells into stem cells that resemble those of a younger state. Retro sees these proteins as critical to its vision of building human organs and generating replacement cells for medical applications.

While Google’s Nobel prize-winning Alphafold focuses on predicting protein shapes, GPT-4b micro is distinct in its approach by emphasizing the re-engineering of proteins. This innovative direction highlights OpenAI’s tailored efforts to address complex biological challenges through machine learning.

The collaboration aims to advance longevity science by leveraging AI’s capability to analyze and model biological data at an unprecedented scale. OpenAI and Retro Biosciences have announced plans to release research findings on the model’s performance and its contributions to the field.


Edited by Harshajit Sarmah